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Quick Links What is Celadrin? What is Celadrin made from? Is Celadrin Safe? How does Celadrin work? Is there any science behind Celadrin®? Which is better, Celadrin cream or Celadrin® pills? How would you compare Vioxx and other Cox 2 - Inhibitors to Celadrin®? How does Celadrin® compare to other natural joint health products? Can Celadrin® work well in conjunction to taking Glucosamine? Does Celadrin replace fish oils? Does Celadrin work like Vioxx and Celabrex? Can I take Celadrin with Coumadin (Warfarin)?   Since using the cream, the pain has been completely eliminated. It is quite astounding. I can't tell enough people about this amazing product. Ken C. Coronado, CA 92118 What is Celadrin? Celadrin® is one of the newest, most effective natural anti-inflammatory compounds that safely promotes flexibility and healthy joint function. Published clinical studies have reported significant results without any side effects. What is Celadrin® made from? Celadrin® is made from a patented complex blend of special esterified fatty acids oil. Is Celadrin® Safe? Celadrin® is a very safe mix of fatty acids with no known or reported negative reactions or side effects in clinical studies. The esterification process takes place at extremely high temperatures (over 500 degrees Fahrenheit). Scientific Acute Toxicity and Ames test screening have validated its safety. Over 1/2 billion Celadrin® pills have been distributed to date. How does Celadrin® work? Celadrin® decreases inflammation and lubricates cell membranes throughout the body, restoring fluids that cushion bones and joints to promote flexibility and mobility. Over time, because of the reduction of inflammation delivered by using Celadrin® the joints and surrounding tissue have an opportunity to promote healthy joints. Celadrin® works similar to, but much more dramatically than the essential fatty acids EPA and DHA from fish oils. Celadrin's complex blend of esterified fatty acids; provide many vital and beneficial effects for the inflammatory responses in the body. Celadrin® induces changes at the cellular level, in the cell membranes which positively affect the responsiveness of the cell membranes. This aids in the reduction of cartilage breakdown in the joints. Is there any science behind Celadrin®? Celadrin® has been clinically studied at various times with results published in the prestigious Journal of Rheumatology for both oral and topical applications as well as the Journal of Strength and Conditioning Research. For oral application, Celadrin® was studied using a double blind, multi-center, placebo-controlled trial (the most scientifically validated type). Sixty-four participants between the ages of 37 to 77 were given Celadrin® capsules and were evaluated at the beginning of the trial, at 30 days and at the end of the 68 day study. Compared to those given a placebo, those who were given Celadrin® had more flexibility, fewer aches, less pain and were able to walk further distances than the placebo group. The study therefore concluded that Celadrin® when taken orally improved joint and mobility problems. The clinical was published in the prestigious and intently acclaimed Journal of Rheumatology. For topical application of Celadrin® cream, a study was conducted at the University of Connecticut, involving 42 patients with osteoarthritis of the knee. Participants used either Celadrin® or a placebo cream. Patients were evaluated before application of the cream, 30 minutes after, and then again following a 30 day treatment period during which the cream was applied twice a day, morning and evening. The researchers evaluated physical function, postural movement, pain and range of motion. The test included how long it took the patient to get up and go from a chair, stair climbing, endurance, and mobility of the knee. The group receiving Celadrin® had outstanding results with reduced pain and stiffness, improved balance and strength and better mobility. 100% of the patients in the study showed significant benefit compared to the patients on the placebo. Even more exiting was that patients experienced a dramatic improvement in all aspects tested after only 30 minutes of applying the cream with cumulative benefits occurring after 30 days. An additional published study, as an extension of this original study, confirmed earlier research showing improvement in elbow, wrist and knee mobility and significant reduction in pain. Which is better, Celadrin® cream or Celadrin® pills? Both oral and topical applications were shown to be equally effective. In a separate study, it was proven that the Esterified Fatty Acids (EFAC) found in Celadrin® could be absorbed by either method (95.1% absorption rate proven through a University of Minnesota labeled study) into the body. How would you compare Vioxx and other Cox 2 - Inhibitors to Celadrin®? Vioxx works as a Cox-2 inhibitor, which causes numerous side effects - including upper and lower G.I. bleeding amongst other even more serious side effects. The whole class of Cox-2 inhibitors raises doubts about their safety. These drugs were supposed to offer the pain killing features of aspirin without damage to the stomach lining. When taking Vioxx or other Cox-2s, one only receives pain relief for a short period of time. Celadrin® helps relieve the stiffened membrane caused by aging, inflammation and other assaults. Restoration and joint health begins with Celadrin® where it has immediate and cumulative benefits, with no negative side effects. Safety profile of Celadrin® is impeccable. With Celadrin®, one is better off tomorrow and the next day than they are today - it just gets better every day as Celadrin® addresses causation, not just the symptoms. Celadrin® works on the cell membrane to allow rapid healing - you don't need glucosamine to repair cartilage, Celadrin® provides the mobility of the joint and surrounding tendons and tissues. One does not need the matrix of the bone to repair a broken arm - but with Celadrin® even that broken arm will be repaired faster - naturally. In summary, while the current, popular drug treatments for inflammatory conditions may relieve the pain, some medical professionals believe that these treatments pose other serious health risks, and may actually worsen the underlying condition. Anti-inflammatory drugs and Cox-2 inhibitors may cause negative side effects. Increasingly, people suffering with inflammatory disorders are turning to more natural alternatives encompassing nutrition and regimens that seek to address the underlying chronic process, and in turn provide restorative relief from discomfort and disability. How does Celadrin® compare to other natural joint health products? Celadrin's beneficial effects have been proven superior in results to Glucosamine, Chondroitin, MSM, SAMe and other natural joint health products. Celadrin® provides restoration of a wide range of joint health conditions including sports injuries to joints, muscles, tendons, deep tissue and muscle cramps. Can Celadrin® work well in conjunction to taking Glucosamine? The cause of wear on the joint area can be attributable to inflammation as well as insufficient lubrication and cell membrane fluidity. Glucosamine assists in the rebuilding of cartilage & the overall structure of the joint and has shown moderate effects on people with osteoarthritis. Celadrin® provides continuous lubrication and allows the cell membrane to repel inflammatory chemicals. Celadrin® stops the cascade of inflammation and the assaults on the membrane which cause it to stiffen. Celadrin® empowers glucosamine to perform faster and more efficiently in building joint cartilage as well as accelerating and promoting joint health. The dual action of Celadrin® and glucosamine provide rapid joint cushioning, quickly alleviating inflammation, building cartilage and restoring the entire joint area. Does Celadrin work like Vioxx and Celabrex? No synthetic Cox-2 inhibitors are very specific. In addition to producing inflammatory agents in the body, Cox-2 is required in the manufacture of prostacyclin a very positive prostaglandin. Because Cox-2 uses up this protective prostaglandin this is likely the reason behind its negative effects. Celadrin does not affect prostacylcin and therefore provides a safe, non-toxic anti-inflammatory action. Can I take Celadrin with Coumadin (Warfarin)? One of the most common questions received by the Celadrin® website is about the use of Coumadin or Warfarin and Celadrin®. Celadrin® is a combination of fatty acids. The Physician's Desk Reference (PDR) provides the following advice regarding herb and nutrient consumption while taking Coumadin or Warfarin. The list of those that should be avoided or not to be started once you are on anti-coagulant drugs includes bromelain, coenzyme Q10, danshen, dong quai, garlic, Ginkgo biloba, ginseng and St. John's Wort and vitamin E and vitamin K. Fatty acids (fish oil, Evening Primrose oil, Borage, Cetylated fatty acids, olive oil) are not included.

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